
Cancer is the second leading cause of death worldwide. In every single puff of smoking, more than 80 carcinogens enter the body, directly damaging cellular DNA. Chronic smoking causes an accumulation of genetic mutations in the body's cells, which can ultimately lead to cancer. Recent large-scale studies estimated that 15.1% of new cancers and 21.4% of cancer deaths worldwide are attributed to tobacco use, which is a major preventable risk factor. Quitting smoking can significantly reduce the risks of cancer incidence, progression, mortality, and recurrence, while tobacco control remains the most efficient public health policy for reducing the social cancer burden and protecting public health.
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